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S-adenosylhomocysteine hydrolase-like protein 1

Summary

UniProt ID: O43865
Gene Symbol: AHCYL1 DCAL IRBIT XPVKONA
Gene ID: 10768
Organism: Homo sapiens (human)

External Links

GlyGen: O43865
PubChem: O43865
The Human Metabolome Database: HMDBP00663
Re-Glyco: O43865

Annotation

Keyword: 3D-structure Acetylation Alternative splicing Cell membrane Cytoplasm Microsome NAD One-carbon metabolism Phosphoprotein Proteomics identification RNA-binding Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
protein export from nucleus
one-carbon metabolic process
apoptotic process
positive regulation of sodium ion transport	IMP	PMID
regulation of mRNA 3'-end processing	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

angiotensin-activated signaling pathway

metabolic process [inference]

sulfur compound metabolic process [inference]

S-adenosylmethionine metabolic process [inference]

L-methionine cycle

small molecule metabolic process [inference]

one-carbon metabolic process

cell death [inference]

programmed cell death [inference]

apoptotic process

intercellular transport [inference]

nuclear export [inference]

protein export from nucleus

membrane docking [inference]

organelle localization by membrane tethering [inference]

mitochondrion-endoplasmic reticulum membrane tethering

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

protein export from nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

mitochondrion-endoplasmic reticulum membrane tethering

response to stimulus [inference]

response to chemical [inference]

response to metal ion [inference]

response to calcium ion

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

nuclear export [inference]

protein export from nucleus

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

fluid transport [inference]

epithelial fluid transport

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

protein export from nucleus

transepithelial transport [inference]

epithelial fluid transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

protein export from nucleus

organelle localization [inference]

organelle localization by membrane tethering [inference]

mitochondrion-endoplasmic reticulum membrane tethering

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein export from nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

protein export from nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

regulation of monoatomic anion transport

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

angiotensin-activated signaling pathway

regulation of metabolic process [inference]

regulation of macromolecule metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA 3'-end processing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA 3'-end processing

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
cytoplasm	ISS	GO_REF
endoplasmic reticulum membrane	TAS	Reactome
cytosol	IBA	GO_REF
cytosol	IEA	GO_REF GO_REF
apical plasma membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

plasma membrane region [inference]

apical plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

organelle membrane contact site [inference]

mitochondria-associated endoplasmic reticulum membrane contact site

Displaying **all 3** entries
GO Term	Evidence Code	Reference
RNA binding
enzyme regulator activity	IEA	GO_REF
identical protein binding	IPI	PMID PMID

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding [inference]

identical protein binding

molecular function regulator activity [inference]

enzyme regulator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
279			G15664MX	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 10** entries
Pathway Name	Organism
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Homo sapiens
CLEC7A (Dectin-1) induces NFAT activation	Homo sapiens
DAG and IP3 signaling	Homo sapiens
FCERI mediated Ca+2 mobilization	Homo sapiens
FCGR3A-mediated IL10 synthesis	Homo sapiens
Ion homeostasis	Homo sapiens
PLC beta mediated events	Homo sapiens
Regulation of insulin secretion	Homo sapiens
Role of phospholipids in phagocytosis	Homo sapiens
VEGFR2 mediated cell proliferation	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements