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MIRAGE
Tripeptidyl-peptidase 1

Summary
UniProt ID
O89023
Gene Symbol
  • Cln2
  • Tpp1
Gene ID
12751
Organism
Mus musculus (house mouse)
GlycoProtDB
GPDB0003243
GlyConnect
GlyGen
O89023
PubChem
O89023
The Human Metabolome Database
HMDBP14581
RaftProt
O89023
Re-Glyco
O89023
Annotation
Keyword
  • Autocatalytic cleavage
  • Calcium
  • Disulfide bond
  • Glycoprotein
  • Lysosome
  • Metal-binding
  • Reference proteome
  • Serine protease
  • Signal
  • Zymogen
Gene Ontology (GO)
Displaying all 6 entries
GO Term
mitochondrion
lysosome
melanosome
Golgi apparatus
membrane raft
recycling endosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGLQARLLGLLALVIAGKCTYNPEPDQRWMLPPGWVSLGRVDPEEELSLTFALKQRNLERLSELVQAVSDPSSPQYGKYLTLEDVAELVQPSPLTLLTVQKWLSAAGARNCDSVTTQDFLTCWLSVRQAELLLPGAEFHRYVGGPTKTHVIRSPHPYQLPQALAPHVDFVGGLHRFPPSSPRQRPEPQQVGTVSLHLGVTPSVLRQRYNLTAKDVGSGTTNNSQACAQFLEQYFHNSDLTEFMRLFGGSFTHQASVAKVVGKQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHEAQEPFLQWLLLLSNESSLPHVHTVSYGDDEDSLSSIYIQRVNTEFMKAAARGLTLLFASGDTGAGCWSVSGRHKFRPSFPASSPYVTTVGGTSFKNPFLITDEVVDYISGGGFSNVFPRPPYQEEAVAQFLKSSSHLPPSSYFNASGRAYPDVAALSDGYWVVSNMVPIPWVSGTSASTPVFGGILSLINEHRILNGRPPLGFLNPRLYQQHGTGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
209 N-linked (GlcNAc...) asparagine
221 N-linked (GlcNAc...) (high mannose) asparagine
285 N-linked (GlcNAc...) asparagine
312 N-linked (GlcNAc...) asparagine
442 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0110726 neuronal ceroid lipofuscinosis 2
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025