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Cytochrome P450 1A2

Summary

UniProt ID

P00186

Gene Symbol

Cyp1a2
Cyp1a-2

Organism

Mus musculus (house mouse)

External Links

PubChem: P00186

Annotation

Keyword

Direct protein sequencing
Fatty acid metabolism
Glycoprotein
Heme
Lyase
Membrane
Microsome
Monooxygenase
Reference proteome
Sterol metabolism

Gene Ontology (GO)

Displaying entries **1 - 10** of 23 in total

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GO Term
monoterpenoid metabolic process
dibenzo-p-dioxin metabolic process
arachidonic acid metabolic process
porphyrin-containing compound metabolic process
xenobiotic metabolic process
cholesterol metabolic process
xenobiotic catabolic process
cellular respiration
estrogen metabolic process
toxin biosynthetic process

Displaying **all 2** entries
GO Term
intracellular membrane-bounded organelle
endoplasmic reticulum membrane

Displaying entries **1 - 10** of 14 in total

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GO Term
heme binding
nitrite reductase (NO-forming) activity
17-alpha-hydroxyprogesterone aldolase activity
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
aromatase activity
steroid 17-alpha-monooxygenase activity
demethylase activity
caffeine oxidase activity
estrogen 16-alpha-hydroxylase activity

Annotation information from UniProt.

Sequence

MAFSQYISLAPELLLATAIFCLVFWMVRASRTQVPKGLKNPPGPWGLPFIGHMLTVGKNPHLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSASSCYLEEHVSKEANHLVSKLQKAMAEVGHFEPVSQVVESVANVIGAMCFGKNFPRKSEEMLNIVNNSKDFVENVTSGNAVDFFPVLRYLPNPALKRFKTFNDNFVLFLQKTVQEHYQDFNKNSIQDITSALFKHSENYKDNGGLIPEEKIVNIVNDIFGAGFDTVTTAITWSILLLVTWPNVQRKIHEELDTVVGRDRQPRLSDRPQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKERCIYINQWQVNHDEKQWKDPFVFRPERFLTNNNSAIDKTQSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLQHLEFSVPPGVKVDLTPNYGLTMKPGTCEHVQAWPRFSK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
68	O-linked (GlcNAc) serine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Aflatoxin activation and detoxification	Mus musculus
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	Mus musculus
Biosynthesis of maresin-like SPMs	Mus musculus
Biosynthesis of protectins	Mus musculus
Methylation	Mus musculus
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Mus musculus
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Mus musculus