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Aflatoxin activation and detoxification

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-5423646

PubChem

R-MMU-5423646

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 11 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P00186	Cytochrome P450 1A2	Cyp1a-2 Cyp1a2	view
P15392	Cytochrome P450 2A4	Cyp2a-4 Cyp2a4	view
P20852	Cytochrome P450 2A5	Cyp2a-5 Cyp2a5	view
P31428	Dipeptidase 1	Dpep1 Mbd1 Rdp	view
P56593	Cytochrome P450 2A12	Cyp2a12	view
Q60928	Glutathione hydrolase 1 proenzyme	Ggt Ggt1 Ggtp	view
Q6PDE7	Glutathione hydrolase 6	Ggt6	view
Q8C255	Dipeptidase 2	Dpep2 Mbd2	view
Q99JP7	Glutathione hydrolase 7	Ggt7 Ggtl3	view
Q99JW2	Aminoacylase-1	Acy1	view

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