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Interleukin-1 alpha
Summary
- UniProt ID
- P01583
- Gene Symbol
-
- IL1A
- IL1F1
- Gene ID
- 3552
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cytokine
- Cytoplasm
- Direct protein sequencing
- Glycoprotein
- Mitogen
- Myristate
- Nucleus
- Phosphoprotein
- Pyrogen
- Reference proteome
- Secreted
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| cell surface |
| extracellular region |
| extracellular space |
| nucleus |
| GO Term |
|---|
| response to copper ion |
| extrinsic apoptotic signaling pathway in absence of ligand |
| GO Term |
|---|
| interleukin-1 receptor binding |
| cytokine activity |
| copper ion binding |
Sequence
MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-1 processing | Homo sapiens |
| Interleukin-1 signaling | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Purinergic signaling in leishmaniasis infection | Homo sapiens |
| Pyroptosis | Homo sapiens |
| Senescence-Associated Secretory Phenotype (SASP) | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081267 | graft-versus-host disease | |
| DOID:10126 | keratoconus | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11476 | osteoporosis | |
| DOID:14499 | Fabry disease | |
| DOID:2841 | asthma | |
| DOID:3082 | interstitial lung disease | |
| DOID:3770 | pulmonary fibrosis | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:4371 | Schnitzler syndrome |
