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Ig gamma-1 chain C region, membrane-bound form

Summary

UniProt ID

P01869

Gene Symbol

Igh-4
Ighg1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P01869
Re-Glyco: P01869

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
extracellular space
cytoplasm
immunoglobulin complex, circulating
external side of plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 13 in total

1

2

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GO Term
complement activation, classical pathway
phagocytosis, recognition
phagocytosis, engulfment
immunoglobulin mediated immune response
B cell differentiation
defense response to bacterium
positive regulation of phagocytosis
positive regulation of immune response
antibacterial humoral response
positive regulation of type IIa hypersensitivity

Displaying **all 2** entries
GO Term
antigen binding
immunoglobulin receptor binding

Annotation information from UniProt.

Sequence

AKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICTVPEVSSVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVEVHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNSAAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMITDFFPEDITVEWQWNGQPAENYKNTQPIMNTNGSYFVYSKLNVQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
174			G42124LM G23863VK G78059CC G27919IH G46687AB G58667NI G49874UX G80858MF	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Classical antibody-mediated complement activation	Mus musculus
FCGR activation	Mus musculus
Initial triggering of complement	Mus musculus
Regulation of Complement cascade	Mus musculus
Regulation of actin dynamics for phagocytic cup formation	Mus musculus
Role of phospholipids in phagocytosis	Mus musculus