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Putative HLA class I histocompatibility antigen, alpha chain H

Summary

UniProt ID

P01893

Gene Symbol

HLA-H
HLAH

Organism

Homo sapiens (human)

External Links

GlyGen: P01893
Re-Glyco: P01893

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
MHC I
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

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GO Term
Golgi membrane
external side of plasma membrane
cell surface
ER to Golgi transport vesicle membrane
early endosome membrane
recycling endosome membrane
extracellular space
plasma membrane
phagocytic vesicle membrane
lumenal side of endoplasmic reticulum membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 4** entries
GO Term
immune response
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

Displaying **all 3** entries
GO Term
signaling receptor binding
peptide antigen binding
beta-2-microglobulin binding

Annotation information from UniProt.

Sequence

MVLMAPRTLLLLLSGALALTQTWARSHSMRYFYTTMSRPGAGEPRFISVGYVDDTQFVRFDSDDASPREEPRAPWMEREGPKYWDRNTQICKAQAQTERENLRIALRYYNQSEGGSHTMQVMYGCDVGPDGPFLRGYEQHAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAARRAEQRRVYLEGEFVEWLRRYLENGKETLQRADPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWEPSSQPTVPIVGIVAGLVLLVAVVTGAVVAAVMWRKKSSDRKGGSYSQAASSNSAQGSDVSLTA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
110	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Homo sapiens
ER-Phagosome pathway	Homo sapiens
Endosomal/Vacuolar pathway	Homo sapiens
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Homo sapiens
Interferon alpha/beta signaling	Homo sapiens
Interferon gamma signaling	Homo sapiens
Neutrophil degranulation	Homo sapiens
SARS-CoV-2 activates/modulates innate and adaptive immune responses	Homo sapiens