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Estrogen receptor

Summary

UniProt ID

P06211

Gene Symbol

Esr1
Esr
Estr
Nr3a1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P06211

Annotation

Keyword

Activator
Cell membrane
Cytoplasm
DNA-binding
Glycoprotein
Golgi apparatus
Methylation
Nucleus
Palmitate
Phosphoprotein
Receptor
Reference proteome
Steroid-binding
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

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GO Term
intracellular estrogen receptor signaling pathway
response to estrogen
positive regulation of epidermal growth factor receptor signaling pathway
decidualization
negative regulation of transcription by RNA polymerase II
regulation of DNA-templated transcription
regulation of transcription by RNA polymerase II
antral ovarian follicle growth
epithelial cell development
osteoblast development

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GO Term
T-tubule
perikaryon
transcription regulator complex
perinuclear region of cytoplasm
nucleus
chromatin
euchromatin
cytoplasm
Golgi apparatus
plasma membrane

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GO Term
nuclear estrogen receptor activity
nuclear estrogen receptor binding
type 1 metabotropic glutamate receptor binding
identical protein binding
DNA-binding transcription activator activity, RNA polymerase II-specific
nuclear receptor activity
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
TFIIB-class transcription factor binding

Annotation information from UniProt.

Sequence

MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPAVFNYPEGAAYEFNAAAAAAAAGASAPVYGQSSITYGPGSEAAAFGANSLGAFPQLNSVSPSPLMLLHPPPHVSPFLHPHGHQVPYYLENEPSAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSSEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGTSGDMRAANLWPSPLVIKHTKKNSPALSLTADQMVSALLDAEPPLIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKINDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAPASRMGVPPEEPSQSQLTTTSSTSAHSLQTYYIPPEAEGFPNTI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
10	O-linked (GlcNAc) serine			UniProt
576	O-linked (GlcNAc) threonine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
ESR-mediated signaling	Rattus norvegicus
Estrogen-dependent gene expression	Rattus norvegicus
Extra-nuclear estrogen signaling	Rattus norvegicus
Nuclear Receptor transcription pathway	Rattus norvegicus
Nuclear signaling by ERBB4	Rattus norvegicus
Ovarian tumor domain proteases	Rattus norvegicus
PI3K/AKT Signaling	Rattus norvegicus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Rattus norvegicus
RUNX1 regulates estrogen receptor mediated transcription	Rattus norvegicus
SUMOylation of intracellular receptors	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Annotation

International Collaboration

Acknowledgements