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MIRAGE
Immunoglobulin heavy constant epsilon
Summary
- UniProt ID
- P06336
- Gene Symbol
- IGHE
- Gene ID
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- 3D-structure Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Secreted
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| antibody-dependent cellular cytotoxicity | ||
| positive regulation of type I hypersensitivity | ||
| serotonin secretion | ||
| B cell antigen processing and presentation | ||
| humoral immune response mediated by circulating immunoglobulin |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| obsolete extracellular space |
|
|
| cytoplasm | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| antigen binding | ||
| antigen binding | ||
| immunoglobulin receptor binding | ||
| immunoglobulin receptor binding | ||
| immunoglobulin receptor binding |
Sequence
SIRNPQLYPLKPCKGTASMTLGCLVKDYFPNPVTVTWYSDSLNMSTVNFPALGSELKVTTSQVTSWGKSAKNFTCHVTHPPSFNESRTILVRPVNITEPTLELLHSSCDPNAFHSTIQLYCFIYGHILNDVSVSWLMDDREITDTLAQTVLIKEEGKLASTCSKLNITEQQWMSESTFTCKVTSQGVDYLAHTRRCPDHEPRGVITYLIPPSPLDLYQNGAPKLTCLVVDLESEKNVNVTWNQEKKTSVSASQWYTKHHNNATTSITSILPVVAKDWIEGYGYQCIVDHPDFPKPIVRSITKTPGQRSAPEVYVFPPPEEESEDKRTLTCLIQNFFPEDISVQWLGDGKLISNSQHSTTTPLKSNGSNQGFFIFSRLEVAKTLWTQRKQFTCQVIHEALQKPRKLEKTISTSLGNTSLRPS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 43 |
|
|
||
| 72 |
|
|
||
| 84 |
|
|
||
| 95 |
|
|
||
| 166 |
|
|
||
| 238 |
|
|
||
| 261 |
|
|
||
| 365 |
|
|
||
| 415 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FCERI mediated Ca+2 mobilization | Mus musculus |
| FCERI mediated MAPK activation | Mus musculus |
| FCERI mediated NF-kB activation | Mus musculus |
| Fc epsilon receptor (FCERI) signaling | Mus musculus |
| Role of LAT2/NTAL/LAB on calcium mobilization | Mus musculus |
