GlyCosmos Portal

Submissions

FCERI mediated MAPK activation

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-2871796

PubChem

R-MMU-2871796

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 9** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O88643	Serine/threonine-protein kinase PAK 1	Pak1 Paka	view
P01101	Protein c-Fos	Fos	view
P05627	Transcription factor Jun	Jun	view
P06336	Immunoglobulin heavy constant epsilon	IGHE	view
P20489	High affinity immunoglobulin epsilon receptor subunit alpha	Fce1a Fcer1a	view
P25911	Tyrosine-protein kinase Lyn	Lyn	view
P32883	GTPase KRas	Kras Kras2	view
P47809	Dual specificity mitogen-activated protein kinase kinase 4	Jnkk1 Map2k4 Mek4 Mkk4 Prkmk4 Sek1 Serk1 Skk1	view
Q8CIN4	Serine/threonine-protein kinase PAK 2	Pak2	view

If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".

About Release Notes Help Feedback

Click here to visit the beta site.