Adenine phosphoribosyltransferase

Summary
UniProt ID
P07741
Gene Symbol
  • APRT
Gene ID
353
Organism
Homo sapiens (human)
GlyGen
P07741
PubChem
P07741
The Human Metabolome Database
HMDBP00438
RaftProt
P07741
Re-Glyco
P07741
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Glycosyltransferase
  • Phosphoprotein
  • Purine salvage
  • Reference proteome
Gene Ontology (GO)
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Sequence
MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
21
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Defective APRT disrupts adenine salvage Homo sapiens
Neutrophil degranulation Homo sapiens
Purine salvage Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0060350 adenine phosphoribosyltransferase deficiency

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025