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Cholesteryl ester transfer protein

Summary

UniProt ID: P11597
Gene Symbol: CETP hCG_23902
Gene ID: 1071
Organism: Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011502

GlyConnect

Cholesteryl ester transfer protein

GlyGen

P11597

PubChem

P11597

SwissLipids

SLP:000000472

The Human Metabolome Database

HMDBP01622

Re-Glyco

P11597

Annotation

Keyword: 3D-structure Alternative splicing Atherosclerosis Cholesterol metabolism Direct protein sequencing Disease variant Disulfide bond Glycoprotein Lipid transport Proteomics identification Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 35 in total

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GO Term	Evidence Code	Reference
triglyceride metabolic process	IDA	PMID
triglyceride metabolic process	IBA	GO_REF
lipid transport	IDA	PMID
cholesterol metabolic process	IDA	PMID
cholesterol metabolic process	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis

acylglycerol homeostasis [inference]

triglyceride homeostasis

phospholipid homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport

sterol transport [inference]

cholesterol transport

reverse cholesterol transport

acylglycerol transport [inference]

triglyceride transport

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport

reverse cholesterol transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

positive regulation of phospholipid transport

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

regulation of cholesterol transport [inference]

regulation of phospholipid transport [inference]

positive regulation of phospholipid transport

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

positive regulation of phospholipid transport

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

positive regulation of phospholipid transport

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

regulation of cholesterol transport [inference]

regulation of phospholipid transport [inference]

positive regulation of phospholipid transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

positive regulation of phospholipid transport

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

positive regulation of phospholipid transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport

positive regulation of phospholipid transport

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of macrophage derived foam cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

regulation of macrophage derived foam cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

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GO Term	Evidence Code	Reference
extracellular region	EXP	PMID
extracellular region	TAS	Reactome Reactome Reactome Reactome
extracellular region	IDA	PMID PMID
extracellular region	IEA	GO_REF
obsolete extracellular space

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

extracellular protein-containing complex [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

cellular anatomical structure [inference]

extracellular region

organelle [inference]

membrane-bounded organelle [inference]

vesicle

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
obsolete phospholipid transporter activity
lipid binding	IDA	PMID
lipid binding	IEA	GO_REF
cholesterol binding	IDA	PMID
cholesterol binding	IBA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

lipid transfer activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

binding [inference]

lipid binding

steroid binding [inference]

sterol binding [inference]

cholesterol binding

phospholipid binding [inference]

phosphatidylcholine binding

triglyceride binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

phosphatidylcholine binding

alcohol binding [inference]

cholesterol binding

quaternary ammonium group binding [inference]

phosphatidylcholine binding

molecular carrier activity [inference]

lipid carrier activity [inference]

lipid transfer activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
105	N-linked (GlcNAc...) (complex) asparagine	19139490 29391424 37074911	G15169WU G47518TP G52527GH G22310AV G45395BF G59536GA G48414YA G27058EU	UniProt GlyGen GlyConnect
257	N-linked (GlcNAc...) asparagine	16335952 37074911	G45395BF G27058EU G90659AW	GlycoProtDB UniProt GlyGen
266		30459171	G43417UB	GlyGen
358	N-linked (GlcNAc...) asparagine	16335952 23090970 29391424 37074911	G86795LJ G52527GH G14796IU G00912UN G59626AS G10486CT	UniProt GlyGen GlyConnect
413	N-linked (GlcNAc...) asparagine			UniProt GlyGen