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MIRAGE
Fibroblast growth factor receptor 1
Summary
- UniProt ID
- P16092
- Gene Symbol
- Fgfr1 Flg
- Gene ID
- 14182
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003422
- GlyConnect
- GlyGen
- P16092
- PubChem
- P16092
- The O-GlcNAc Database
- P16092
- Re-Glyco
- P16092
Annotation
- Keyword
- 3D-structure ATP-binding Alternative splicing Cell membrane Cytoplasm Cytoplasmic vesicle Disulfide bond Glycoprotein Heparin-binding Immunoglobulin domain Nucleus Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| angiogenesis | ||
| ureteric bud development | ||
| in utero embryonic development | ||
| organ induction |
GO Hierarchy
- regulation of phosphorus metabolic process
biological process
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of growth [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell population proliferation
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell cycle [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein tyrosine kinase activity | ||
| protein tyrosine kinase activity | ||
| fibroblast growth factor receptor activity | ||
| fibroblast growth factor receptor activity | ||
| fibroblast growth factor receptor activity |
GO Hierarchy
Sequence
MWGWKCLLFWAVLVTATLCTARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQSINWLRDGVQLVESNRTRITGEEVEVRDSIPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMLGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSIPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPTQLANSGLKRR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 76 |
|
|||
| 77 |
|
|||
| 117 |
|
|
||
| 227 |
|
|
||
| 240 |
|
|
||
| 264 |
|
|||
| 296 |
|
|||
| 317 |
|
|||
| 330 |
|
|
||
| 724 |
|
G49108TO
G87389XI
G33609NS
G80223IX
G10773YW
G80920RR
G82119TF
G06110VR
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signaling of activated FGFR1 | Mus musculus |
| FGFR1b ligand binding and activation | Mus musculus |
| FGFR1c and Klotho ligand binding and activation | Mus musculus |
| FGFR1c ligand binding and activation | Mus musculus |
| FRS-mediated FGFR1 signaling | Mus musculus |
| Negative regulation of FGFR1 signaling | Mus musculus |
| PI-3K cascade:FGFR1 | Mus musculus |
| PI3K Cascade | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
