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Cathepsin D

Summary

UniProt ID

P18242

Gene Symbol

Ctsd

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003450

GlyConnect

2190

GlyGen

P18242

PubChem

P18242

The O-GlcNAc Database

P18242

RaftProt

P18242

O-GlcNAcAtlas

P18242

Annotation

Keyword

Aspartyl protease
Disulfide bond
Glycoprotein
Lysosome
Reference proteome
Secreted
Signal
Zymogen

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
autophagosome assembly
proteolysis
protein catabolic process
insulin receptor recycling
lipoprotein catabolic process
positive regulation of apoptotic process
regulation of establishment of protein localization
insulin catabolic process

Displaying entries **1 - 10** of 11 in total

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GO Term
extracellular space
lysosome
lysosomal membrane
melanosome
presynaptic endosome
collagen-containing extracellular matrix
GABA-ergic synapse
endosome lumen
mitochondrion
membrane raft

Displaying **all 6** entries
GO Term
peptidase activity
hydrolase activity
peptide binding
endopeptidase activity
aspartic-type endopeptidase activity
aspartic-type peptidase activity

Annotation information from UniProt.

Sequence

MKTPGVLLLILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVGFANAVVL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
134	N-linked (GlcNAc...) asparagine		G05724UK G39188ZX G41247ZX G06110VR	UniProt GlyGen GlyConnect
258			G49108TO	GlyGen The O-GlcNAc Database
261	N-linked (GlcNAc...) (high mannose) asparagine	16170054	G84820NF G11870QZ G05724UK G93180LE G39188ZX G41247ZX G25637MV G06110VR G00406II G66538GV G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
263			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Collagen degradation	Mus musculus
Insulin receptor recycling	Mus musculus
MHC class II antigen presentation	Mus musculus
Metabolism of Angiotensinogen to Angiotensins	Mus musculus
Neutrophil degranulation	Mus musculus