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Metabolism of Angiotensinogen to Angiotensins

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-2022377

PubChem

R-MMU-2022377

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 13 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P06281	Renin-1	Ren Ren-1 Ren1	view
P09470	Angiotensin-converting enzyme	Ace Dcp1	view
P11859	Angiotensinogen	Agt Serpina8	view
P15089	Mast cell carboxypeptidase A	Cpa3	view
P16406	Glutamyl aminopeptidase	Enpep	view
P18242	Cathepsin D	Ctsd	view
P21844	Chymase	Cma1 Mcpt5	view
P28293	Cathepsin G	Ctsg	view
Q61391	Neprilysin	Mme	view
Q8R0I0	Angiotensin-converting enzyme 2	Ace2	view

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