Plasminogen activator inhibitor 1

Summary
UniProt ID
P20961
Gene Symbol
Pai1 Planh1 Serpine1
Gene ID
24617
Organism
Rattus norvegicus (Norway rat)
PubChem
P20961
Re-Glyco
P20961
Annotation
Keyword
Glycoprotein Reference proteome Secreted Serine protease inhibitor Signal
Gene Ontology (GO)
GO Hierarchy
Sequence
MQMSSALTCLTLGLVLVFGKGFASPLPESHTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERGTAPALRKLSKELMGSWNKNEISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQVDFSEVERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTISVPMMAQNNKFNYTEFTTPDGHEYDILELPYHGETLSMFIAAPFEKDVPLSAITNILDAELIRQWKSNMTRLPRLLILPKFSLETEVDLRGPLEKLGMTDIFSSTQADFTSLSDQEQLSVAQALQKVKIEVNESGTVASSSTAILVSARMAPTEMVLDRSFLFVVRHNPTETILFMGQLMEP
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
88
  • N-linked (GlcNAc...) asparagine
232
  • N-linked (GlcNAc...) asparagine
288
  • N-linked (GlcNAc...) asparagine
352
  • N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Dissolution of Fibrin Clot Rattus norvegicus
ECM proteoglycans Rattus norvegicus
Platelet degranulation Rattus norvegicus
Regulation of clotting cascade Rattus norvegicus
Disease
Displaying entries 1 - 10 of 18 in total
DO ID Disease Name Source
DOID:9352 type 2 diabetes mellitus
DOID:6432 pulmonary hypertension
DOID:783 end stage renal disease
DOID:3627 aortic aneurysm
DOID:0050855 renal fibrosis
DOID:5844 myocardial infarction
DOID:10763 hypertension
DOID:74 hematopoietic system disease
DOID:224 transient cerebral ischemia
DOID:11247 disseminated intravascular coagulation

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026