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Mitogen-activated protein kinase 3

Summary

UniProt ID

P21708

Gene Symbol

Mapk3
Erk1
Prkm3

Organism

Rattus norvegicus (Norway rat)

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell cycle
Cell junction
Cytoplasm
Direct protein sequencing
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
phosphorylation
cartilage development
cardiac neural crest cell development involved in heart development
protein-containing complex assembly
positive regulation of macrophage chemotaxis
Schwann cell development
sensory perception of pain
regulation of ossification
thyroid gland development
cellular response to reactive oxygen species

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GO Term
nucleoplasm
early endosome
late endosome
focal adhesion
protein-containing complex
pseudopodium
glutamatergic synapse
mitochondrion
cytosol
caveola

Displaying **all 10** entries
GO Term
protein kinase activity
protein serine/threonine kinase activity
MAP kinase activity
ATP binding
scaffold protein binding
protein serine kinase activity
DNA-binding transcription factor binding
identical protein binding
phosphatase binding
phosphotyrosine residue binding

Annotation information from UniProt.

Sequence

MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERLKELIFQETARFQPGAPEAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 20** of 41 in total

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Pathway Name	Organism
ISG15 antiviral mechanism	Rattus norvegicus
Interferon gamma signaling	Rattus norvegicus
MAP2K and MAPK activation	Rattus norvegicus
MAPK3 (ERK1) activation	Rattus norvegicus
NCAM signaling for neurite out-growth	Rattus norvegicus
Negative feedback regulation of MAPK pathway	Rattus norvegicus
Negative regulation of FGFR1 signaling	Rattus norvegicus
Negative regulation of FGFR2 signaling	Rattus norvegicus
Negative regulation of FGFR3 signaling	Rattus norvegicus
Negative regulation of FGFR4 signaling	Rattus norvegicus