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Mitogen-activated protein kinase 3

Summary

UniProt ID

P21708

Gene Symbol

Mapk3
Erk1
Prkm3

Organism

Rattus norvegicus (Norway rat)

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell cycle
Cell junction
Cytoplasm
Direct protein sequencing
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
apoptotic process
cell cycle
insulin receptor signaling pathway
response to toxic substance
animal organ morphogenesis
neural crest cell development
phosphorylation
cartilage development
cardiac neural crest cell development involved in heart development
protein-containing complex assembly

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GO Term
nucleus
nuclear envelope
cytoplasm
Golgi apparatus
cytoskeleton
plasma membrane
protein-containing complex
pseudopodium
glutamatergic synapse
mitochondrion

Displaying **all 10** entries
GO Term
protein kinase activity
protein serine/threonine kinase activity
DNA-binding transcription factor binding
identical protein binding
phosphatase binding
phosphotyrosine residue binding
MAP kinase activity
ATP binding
scaffold protein binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERLKELIFQETARFQPGAPEAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **21 - 30** of 41 in total

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Pathway Name	Organism
Negative regulation of MAPK pathway	Rattus norvegicus
Oncogene Induced Senescence	Rattus norvegicus
Oxidative Stress Induced Senescence	Rattus norvegicus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Rattus norvegicus
RAF-independent MAPK1/3 activation	Rattus norvegicus
RAF/MAP kinase cascade	Rattus norvegicus
RHO GTPases Activate NADPH Oxidases	Rattus norvegicus
RHO GTPases Activate WASPs and WAVEs	Rattus norvegicus
RNA Polymerase I Promoter Opening	Rattus norvegicus
Regulation of HSF1-mediated heat shock response	Rattus norvegicus