Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
Interleukin-10
Summary
- UniProt ID
- P22301
- Gene Symbol
-
- IL10
- Gene ID
- 3586
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytokine
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| GO Term |
|---|
| interleukin-10 receptor binding |
| cytokine activity |
| growth factor activity |
| protein dimerization activity |
Sequence
MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 134 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CD163 mediating an anti-inflammatory response | Homo sapiens |
| FCGR3A-mediated IL10 synthesis | Homo sapiens |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Signaling by ALK fusions and activated point mutants | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1470 | major depressive disorder | |
| DOID:1474 | aggressive periodontitis | |
| DOID:1588 | thrombocytopenia | |
| DOID:1793 | pancreatic cancer | |
| DOID:1883 | hepatitis C | |
| DOID:2043 | hepatitis B | |
| DOID:219 | colon cancer | |
| DOID:2349 | arteriosclerosis | |
| DOID:2841 | asthma | |
| DOID:2862 | glucosephosphate dehydrogenase deficiency |
