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Protein Wnt-5a
Summary
- UniProt ID
- P22725
- Gene Symbol
- Wnt5a Wnt-5a
- Gene ID
- 22418
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003491
- GlyGen
- P22725
- PubChem
- P22725
- Re-Glyco
- P22725
Annotation
- Keyword
- Alternative splicing Chondrogenesis Developmental protein Differentiation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Signal Wnt signaling pathway
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| ameboidal-type cell migration | ||
| establishment of planar polarity | ||
| somitogenesis | ||
| positive regulation of cytokine production | ||
| kidney development |
GO Hierarchy
- regulation of synaptic signaling by nitric oxide
- positive regulation of ossification
- positive regulation of cartilage development
- regulation of synaptic signaling by nitric oxide
- positive regulation of ossification
- positive regulation of cartilage development
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of growth [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of signaling [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular component organization [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular component organization [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| signaling receptor binding | ||
| signaling receptor binding | ||
| signaling receptor binding | ||
| frizzled binding | ||
| frizzled binding |
GO Hierarchy
Sequence
MKKPIGILSPGVALGTAGGAMSSKFFLMALATFFSFAQVVIEANSWWSLGMNNPVQMSEVYIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 114 |
|
|||
| 120 |
|
|
||
| 312 |
|
|||
| 326 |
|
|
G80920RR
G07755XJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Asymmetric localization of PCP proteins | Mus musculus |
| Ca2+ pathway | Mus musculus |
| Cargo recognition for clathrin-mediated endocytosis | Mus musculus |
| Clathrin-mediated endocytosis | Mus musculus |
| PCP/CE pathway | Mus musculus |
| TCF dependent signaling in response to WNT | Mus musculus |
| WNT ligand biogenesis and trafficking | Mus musculus |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | Mus musculus |
| WNT5A-dependent internalization of FZD4 | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060254 | Robinow syndrome |
