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WNT5A-dependent internalization of FZD4

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-5099900

PubChem

R-MMU-5099900

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 10** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O08585	Clathrin light chain A	Clta	view
P17426	AP-2 complex subunit alpha-1	Adtaa Ap2a1 Clapa1	view
P17427	AP-2 complex subunit alpha-2	Adtab Ap2a2	view
P22725	Protein Wnt-5a	Wnt-5a Wnt5a	view
P63318	Protein kinase C gamma type	Pkcc Pkcg Prkcc Prkcg	view
P68404	Protein kinase C beta type	Pkcb Prkcb Prkcb1	view
P84091	AP-2 complex subunit mu	Ap2m1 Clapm1	view
Q61088	Frizzled-4	Fzd4	view
Q68FD5	Clathrin heavy chain 1	Cltc	view
Q9DBG3	AP-2 complex subunit beta	Ap2b1 Clapb1	view

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