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GALAXY
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MIRAGE
Frizzled-4
Summary
- UniProt ID
- Q61088
- Gene Symbol
- Fzd4
- Gene ID
- 14366
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0005450
- PubChem
- Q61088
- Re-Glyco
- Q61088
Annotation
- Keyword
- Cell membrane Developmental protein Disulfide bond G-protein coupled receptor Glycoprotein Reference proteome Signal Transmembrane helix Ubl conjugation Wnt signaling pathway
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| angiogenesis | ||
| angiogenesis | ||
| luteinization | ||
| blood vessel development | ||
| vasculogenesis |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| nucleoplasm | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| amyloid-beta binding | ||
| amyloid-beta binding | ||
| cytokine receptor activity | ||
| cytokine receptor activity | ||
| G protein-coupled receptor activity |
|
|
GO Hierarchy
Sequence
MAWPGTGPSSRGAPGGVGLRLGLLLQFLLLLRPTLGFGDEEERRCDPIRIAMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLREFGFAWPDTLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGSNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTTFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNGWVKPGKGNETVV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 59 |
|
|
||
| 144 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Asymmetric localization of PCP proteins | Mus musculus |
| Ca2+ pathway | Mus musculus |
| Cargo recognition for clathrin-mediated endocytosis | Mus musculus |
| Clathrin-mediated endocytosis | Mus musculus |
| Regulation of FZD by ubiquitination | Mus musculus |
| WNT5A-dependent internalization of FZD4 | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050535 | exudative vitreoretinopathy | |
| DOID:0060844 | Norrie disease |
