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AP-2 complex subunit beta

Summary

UniProt ID: Q9DBG3
Gene Symbol: Ap2b1 Clapb1
Gene ID: 71770
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q9DBG3
PubChem: Q9DBG3
RaftProt: Q9DBG3
O-GlcNAcAtlas: Q9DBG3
Re-Glyco: Q9DBG3

Annotation

Keyword: 3D-structure Acetylation Alternative splicing Cell membrane Coated pit Endocytosis Phosphoprotein Protein transport Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	Reference
kidney development	IMP	PMID
cardiac septum development	IMP	PMID
ventricular septum development	IMP	PMID
intracellular protein transport	IEA	GO_REF
neurotransmitter secretion	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization [inference]

neurotransmitter receptor internalization [inference]

postsynaptic neurotransmitter receptor internalization

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

postsynaptic endocytosis [inference]

postsynaptic neurotransmitter receptor internalization

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

postsynaptic endocytosis [inference]

postsynaptic neurotransmitter receptor internalization

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

developmental process [inference]

anatomical structure development [inference]

blood vessel development [inference]

artery development [inference]

aorta development

coronary vasculature development

cardiac septum development

ventricular septum development

animal organ development [inference]

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

protein transport [inference]

intracellular protein transport

vesicle-mediated transport

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization [inference]

neurotransmitter receptor internalization [inference]

postsynaptic neurotransmitter receptor internalization

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

postsynaptic endocytosis [inference]

postsynaptic neurotransmitter receptor internalization

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

postsynaptic endocytosis [inference]

postsynaptic neurotransmitter receptor internalization

secretion [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

intracellular transport [inference]

intracellular protein transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization [inference]

neurotransmitter receptor internalization [inference]

postsynaptic neurotransmitter receptor internalization

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

postsynaptic endocytosis [inference]

postsynaptic neurotransmitter receptor internalization

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

neurotransmitter secretion

intracellular transport [inference]

intracellular protein transport

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

postsynaptic endocytosis [inference]

postsynaptic neurotransmitter receptor internalization

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane

regulation of protein localization to membrane [inference]

positive regulation of protein localization to membrane

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

positive regulation of protein localization to membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis

positive regulation of protein localization to membrane

positive regulation of transport [inference]

positive regulation of endocytosis

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis

positive regulation of protein localization to membrane

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

positive regulation of protein localization to membrane

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of biological quality [inference]

regulation of postsynaptic membrane neurotransmitter receptor levels [inference]

postsynaptic neurotransmitter receptor internalization

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	Reference
synaptic vesicle	ISO	GO_REF
synaptic vesicle	IEA	GO_REF
cytoplasmic side of plasma membrane	NAS	PMID
clathrin coat	ISO	GO_REF
clathrin coat	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

clathrin coat

AP-type membrane coat adaptor complex [inference]

clathrin adaptor complex

AP-2 adaptor complex

plasma membrane protein complex [inference]

AP-2 adaptor complex

cellular anatomical structure [inference]

extrinsic component of membrane [inference]

extrinsic component of plasma membrane [inference]

extrinsic component of synaptic membrane [inference]

extrinsic component of presynaptic membrane [inference]

extrinsic component of presynaptic endocytic zone membrane

cell junction [inference]

synapse

glutamatergic synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

postsynaptic endocytic zone

Displaying **all 5** entries
GO Term	Evidence Code	Reference
clathrin binding	ISO	GO_REF GO_REF GO_REF
clathrin binding	IBA	GO_REF
clathrin binding	IEA	GO_REF GO_REF
protein-containing complex binding	ISO	GO_REF
protein-containing complex binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

clathrin binding

protein-containing complex binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTTTNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
79	G49108TO	GlyGen
90	G49108TO	GlyGen
682		GlyGen
741	G92275SC	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 10** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
LDL clearance	Mus musculus
MHC class II antigen presentation	Mus musculus
Recycling pathway of L1	Mus musculus
Retrograde neurotrophin signalling	Mus musculus
Trafficking of GluR2-containing AMPA receptors	Mus musculus
VLDLR internalisation and degradation	Mus musculus
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	Mus musculus
WNT5A-dependent internalization of FZD4	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements