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MIRAGE
Metalloproteinase inhibitor 1
Summary
- UniProt ID
- P30120
- Gene Symbol
-
- Timp-1
- Timp1
- Gene ID
- 116510
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Metal-binding
- Metalloprotease inhibitor
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Steroidogenesis
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| basement membrane |
| extracellular space |
| extracellular matrix |
| GO Term |
|---|
| protease binding |
| cytokine activity |
| growth factor activity |
| metalloendopeptidase inhibitor activity |
| zinc ion binding |
| peptidase inhibitor activity |
Sequence
MAPFASLASGILLLLSLIASSKACSCAPTHPQTAFCNSDLVIRAKFMGSPEIIETTLYQRYEIKMTKMLKGFDAVGNATGFRFAYTPAMESLCGYVHKSQNRSEEFLIAGRLRNGNLHITACSFLVPWHNLSPAQQKAFVKTYSAGCGVCTVFPCSAIPCKLESDSHCLWTDQILMGSEKGYQSDHFACLPRNPDLCTWQYLGVSMTRSLPLAKAEA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Rattus norvegicus |
| Platelet degranulation | Rattus norvegicus |
| Post-translational protein phosphorylation | Rattus norvegicus |
| Regulation of IGF Activity by IGFBP | Rattus norvegicus |
| TGFBR3 PTM regulation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:90 | degenerative disc disease |
