GlyCosmos Portal

Submissions

Gastrin/cholecystokinin type B receptor

Summary

UniProt ID: P32239
Gene Symbol: CCKBR CCKRB
Gene ID: 887
Organism: Homo sapiens (human)

External Links

PubChem: P32239
The Human Metabolome Database: HMDBP02559
Re-Glyco: P32239

Annotation

Keyword: 3D-structure Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Palmitate Proteomics identification Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	Reference
gastric acid secretion
cell surface receptor signaling pathway	NAS	PMID
phospholipase C-activating G protein-coupled receptor signaling pathway	TAS	PMID
phospholipase C-activating G protein-coupled receptor signaling pathway	IDA	PMID
phospholipase C-activating G protein-coupled receptor signaling pathway	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

gastric acid secretion

developmental process [inference]

anatomical structure development [inference]

tube development [inference]

digestive tract development

animal organ development [inference]

gland development

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

regulation of pH [inference]

pH reduction

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

acid secretion [inference]

gastric acid secretion

biological regulation [inference]

regulation of pH [inference]

pH reduction

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 4** entries
GO Term	Evidence Code	Reference
plasma membrane	TAS	Reactome Reactome Reactome Reactome Reactome
plasma membrane	IDA	PMID GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
cholecystokinin receptor activity	IDA	PMID
cholecystokinin receptor activity	IBA	GO_REF
neuropeptide receptor activity	IBA	GO_REF
gastrin receptor activity	IDA	PMID PMID
gastrin receptor activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

neuropeptide receptor binding [inference]

cholecystokinin receptor binding [inference]

type B gastrin/cholecystokinin receptor binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

molecular function regulator activity [inference]

enzyme regulator activity [inference]

kinase regulator activity [inference]

1-phosphatidylinositol-3-kinase regulator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
7	N-linked (GlcNAc...) asparagine	UniProt
30	N-linked (GlcNAc...) asparagine	UniProt
36	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
G alpha (q) signalling events	Homo sapiens
Gastrin-CREB signalling pathway via PKC and MAPK	Homo sapiens
Peptide ligand-binding receptors	Homo sapiens

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:594	panic disorder	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements