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MIRAGE
GTPase KRas
Summary
- UniProt ID
- P32883
- Gene Symbol
-
- Kras
- Kras2
- Gene ID
- 16653
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Cell membrane
- Cytoplasm
- GTP-binding
- Hydrolase
- Isopeptide bond
- Methylation
- Palmitate
- Prenylation
- Proto-oncogene
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasmic side of plasma membrane |
| cytoplasm |
| plasma membrane |
| endomembrane system |
| membrane |
| GO Term |
|---|
| GTP binding |
| GTPase activity |
| protein-membrane adaptor activity |
| protein-containing complex binding |
| G protein activity |
Sequence
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQELARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCVIM
Glycosylation Sites
G13037JM
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FRS-mediated FGFR2 signaling | Mus musculus |
| FRS-mediated FGFR3 signaling | Mus musculus |
| FRS-mediated FGFR4 signaling | Mus musculus |
| GRB2 events in EGFR signaling | Mus musculus |
| GRB2 events in ERBB2 signaling | Mus musculus |
| MAP2K and MAPK activation | Mus musculus |
| MET activates RAS signaling | Mus musculus |
| NCAM signaling for neurite out-growth | Mus musculus |
| Negative regulation of MAPK pathway | Mus musculus |
| PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:0060581 | Noonan syndrome 3 | |
| DOID:0060688 | arteriovenous malformations of the brain | |
| DOID:10283 | prostate cancer | |
| DOID:1324 | lung cancer | |
| DOID:289 | endometriosis | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:4928 | intrahepatic cholangiocarcinoma |
