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GlyTouCan
Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
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MIRAGE
Catenin beta-1
Summary
- UniProt ID
- P35222
- Gene Symbol
-
- CTNNB
- CTNNB1
- OK/SW-cl.35
- PRO2286
- Gene ID
- 1499
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Cell adhesion
- Cell junction
- Cell membrane
- Cell projection
- Chromosomal rearrangement
- Cytoskeleton
- Disease variant
- Glycoprotein
- Host-virus interaction
- Intellectual disability
- Neurogenesis
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- S-nitrosylation
- Synapse
- Transcription regulation
- Ubl conjugation
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular exosome |
| presynaptic active zone cytoplasmic component |
| postsynaptic density, intracellular component |
| Wnt signalosome |
| Scrib-APC-beta-catenin complex |
| euchromatin |
| nucleus |
| cytoplasm |
| plasma membrane |
| cell-cell junction |
Sequence
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 23 | O-linked (GlcNAc) serine; alternate | |||
| 40 |
|
|||
| 41 |
|
|||
| 112 |
|
|||
| 426 |
|
G49108TO
G59924QI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cardiogenesis | Homo sapiens |
| Deactivation of the beta-catenin transactivating complex | Homo sapiens |
| Degradation of beta-catenin by the destruction complex | Homo sapiens |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | Homo sapiens |
| Formation of axial mesoderm | Homo sapiens |
| Formation of definitive endoderm | Homo sapiens |
| Formation of paraxial mesoderm | Homo sapiens |
| Formation of the beta-catenin:TCF transactivating complex | Homo sapiens |
| Formation of the nephric duct | Homo sapiens |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050902 | medulloblastoma | |
| DOID:0070049 | autosomal dominant intellectual developmental disorder 19 | |
| DOID:0080264 | exudative vitreoretinopathy 7 | |
| DOID:2154 | nephroblastoma | |
| DOID:2394 | ovarian cancer | |
| DOID:5015 | fibrolamellar carcinoma | |
| DOID:5374 | pilomatrixoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9256 | colorectal cancer |
