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MIRAGE
Fibroblast growth factor 8
Summary
- UniProt ID
- P37237
- Gene Symbol
-
- Aigf
- Fgf8
- Gene ID
- 14179
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Developmental protein
- Differentiation
- Direct protein sequencing
- Glycoprotein
- Growth factor
- Mitogen
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| external side of plasma membrane |
| GO Term |
|---|
| growth factor activity |
| chemoattractant activity |
Sequence
MGSPRSALSCLLLHLLVLCLQAQVRSAAQKRGPGAGNPADTLGQGHEDRPFGQRSRAGKNFTNPAPNYPEEGSKEQRDSVLPKVTQRHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| Phospholipase C-mediated cascade: FGFR1 | Mus musculus |
| Phospholipase C-mediated cascade; FGFR2 | Mus musculus |
| Phospholipase C-mediated cascade; FGFR3 | Mus musculus |
| Phospholipase C-mediated cascade; FGFR4 | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
| SHC-mediated cascade:FGFR1 | Mus musculus |
| SHC-mediated cascade:FGFR2 | Mus musculus |
| SHC-mediated cascade:FGFR3 | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11198 | DiGeorge syndrome | |
| DOID:6419 | tetralogy of Fallot |
