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Small ribosomal subunit protein eS19

Summary

UniProt ID: P39019
Gene Symbol: RPS19
Gene ID: 6223
Organism: Homo sapiens (human)

External Links

PubChem: P39019
The O-GlcNAc Database: P39019
RaftProt: P39019
Re-Glyco: P39019

Annotation

Keyword: 3D-structure Acetylation Cytoplasm Diamond-Blackfan anemia Direct protein sequencing Disease variant Host-virus interaction Methylation Nucleus Proteomics identification Reference proteome Ribosomal protein

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	Reference
ribosomal small subunit assembly	IMP	PMID
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IMP	PMID PMID
cytoplasmic translation	NAS	PMID
cytoplasmic translation	IC	PMID
monocyte chemotaxis	IDA	PMID

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

leukocyte migration [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

cellular process [inference]

cell killing [inference]

killing of cells of another organism

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation

cytoplasmic translation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translation

cytoplasmic translation

protein metabolic process [inference]

translation

cytoplasmic translation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

maturation of SSU-rRNA

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

maturation of SSU-rRNA

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

RNA processing [inference]

rRNA processing

maturation of SSU-rRNA

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

protein metabolic process [inference]

translation

cytoplasmic translation

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nucleolus organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

ribosomal small subunit assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

ribosomal small subunit assembly

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

ribosomal small subunit assembly

cellular component biogenesis [inference]

ribonucleoprotein complex biogenesis [inference]

ribosomal small subunit biogenesis

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of immune effector process [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

regulation of immune response [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of respiratory burst [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of multicellular organismal process [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of respiratory burst [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of immune response [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of cellular process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of respiratory burst [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of metabolic process [inference]

positive regulation of respiratory burst [inference]

positive regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst [inference]

regulation of respiratory burst involved in inflammatory response [inference]

positive regulation of respiratory burst [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of respiratory burst [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of cell differentiation [inference]

regulation of cell development [inference]

negative regulation of respiratory burst involved in inflammatory response

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of respiratory burst [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of respiratory burst [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of respiratory burst involved in inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	Reference
nucleoplasm	TAS	Reactome
nucleoplasm	IDA	GO_REF
nucleolus	IDA	PMID PMID PMID
nucleolus	IEA	GO_REF
cytoplasm	EXP	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

small-subunit processome

ribonucleoprotein complex [inference]

preribosome [inference]

small-subunit processome

ribosomal subunit [inference]

small ribosomal subunit [inference]

cytosolic small ribosomal subunit

cellular anatomical structure [inference]

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

ribosome

cytosolic ribosome

intracellular organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

ribosome

cytosolic ribosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

postsynaptic specialization [inference]

postsynaptic density

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
RNA binding	HDA	PMID
structural constituent of ribosome	IDA	PMID
structural constituent of ribosome	IMP	PMID
structural constituent of ribosome	IEA	GO_REF GO_REF
structural constituent of ribosome	HDA	PMID

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of ribosome

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding [inference]

growth factor binding [inference]

fibroblast growth factor binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

identical protein binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
74		20305658 22121020 28510447 29485866 32119511 33214551 34019948 34725712 35138101 37217939 38665916 39395807 40930100	G49108TO	The O-GlcNAc Database
90		20305658 22121020 28510447 29485866 32119511 33214551 34019948 34725712 35138101 37217939 38665916 39395807 40930100	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 20 in total

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Pathway Name	Organism
Eukaryotic Translation Termination	Homo sapiens
Formation of a pool of free 40S subunits	Homo sapiens
Formation of the ternary complex, and subsequently, the 43S complex	Homo sapiens
GTP hydrolysis and joining of the 60S ribosomal subunit	Homo sapiens
L13a-mediated translational silencing of Ceruloplasmin expression	Homo sapiens
Major pathway of rRNA processing in the nucleolus and cytosol	Homo sapiens
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Homo sapiens
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Homo sapiens
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	Homo sapiens
Peptide chain elongation	Homo sapiens

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:1339	Diamond-Blackfan anemia	Alliance of Genome Resources
DOID:0111895	Diamond-Blackfan anemia 1	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements