GlyCosmos Portal

Submissions

Eukaryotic initiation factor 4F subunit p130

Summary

UniProt ID: P39936
Gene Symbol: TIF4632 YGL049C
Gene ID: 852833
Organism: Saccharomyces cerevisiae S288C

External Links

GlyGen: P39936
PubChem: P39936
O-GlcNAcAtlas: P39936
Re-Glyco: P39936

Annotation

Keyword: Cytoplasm Initiation factor Phosphoprotein RNA-binding Reference proteome Translation regulation

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
translational initiation	IDA	PMID
translational initiation	IMP	PMID
translational initiation	IBA	GO_REF
translational initiation	IEA	GO_REF
regulation of translational initiation	NAS	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

translational initiation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

stress granule assembly

cellular component assembly [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

stress granule assembly

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of cytoplasmic translation [inference]

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of cytoplasmic translation [inference]

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of cytoplasmic translation [inference]

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of cytoplasmic translation [inference]

regulation of cytoplasmic translational initiation [inference]

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

regulation of formation of translation preinitiation complex [inference]

positive regulation of formation of translation preinitiation complex

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of formation of translation preinitiation complex

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
P-body	IDA	PMID
P-body	IEA	GO_REF
ribosome	NAS	PMID
cytoplasmic stress granule	IDA	PMID PMID PMID
cytoplasmic stress granule	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

RNA cap binding complex [inference]

eukaryotic translation initiation factor 4F complex

cellular anatomical structure [inference]

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribosome

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

intracellular organelle [inference]

intracellular membraneless organelle [inference]

ribosome

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
ATPase activator activity	ISS	PMID PMID PMID
mRNA binding	IDA	PMID
mRNA binding	HDA	PMID
translation initiation factor activity	IDA	PMID
translation initiation factor activity	IMP	PMID

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding

protein binding [inference]

translation initiation factor binding

molecular function regulator activity [inference]

molecular function activator activity [inference]

ATPase activator activity

translation factor activity [inference]

translation initiation factor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTDQRGPPPPHPQQANGYKKFPPHDNQYSGANNSQPNNHYNENLYSAREPHNNKQYQSKNGKYGTNKYNNRNNSQGNAQYYNNRFNNGYRLNNNDYNPAMLPGMQWPANYYAPQMYYIPQQMVPVASPPYTHQPLNTNPEPPSTPKTTKIEITTKTGERLNLKKFHEEKKASKGEEKNDGVEQKSKSGTPFEKEATPVLPANEAVKDTLTETSNEKSTSEAENTKRLFLEQVRLRKAAMERKKNGLISETEKKQETSNHDNTDTTKPNSVIESEPIKEAPKPTGEANEVVIDGKSGASVKTPQHVTGSVTKSVTFNEPENESSSQDVDELVKDDDTTEISDTTGGKTVNKSDDETINSVITTEENTVKETEPSTSDIEMPTVSQLLETLGKAQPISDIYEFAYPENVERPDIKYKKPSVKYTYGPTFLLQFKDKLKFRPDPAWVEAVSSKIVIPPHIARNKPKDSGRFGGDFRSPSMRGMDHTSSSRVSSKRRSKRMGDDRRSNRGYTSRKDREKAAEKAEEQAPKEEIAPLVPSANRWIPKSRVKKTEKKLAPDGKTELFDKEEVERKMKSLLNKLTLEMFDSISSEILDIANQSKWEDDGETLKIVIEQIFHKACDEPHWSSMYAQLCGKVVKDLDPNIKDKENEGKNGPKLVLHYLVARCHEEFEKGWADKLPAGEDGNPLEPEMMSDEYYIAAAAKRRGLGLVRFIGYLYCLNLLTGKMMFECFRRLMKDLNNDPSEETLESVIELLNTVGEQFEHDKFVTPQATLEGSVLLDNLFMLLQHIIDGGTISNRIKFKLIDVKELREIKHWNSAKKDAGPKTIQQIHQEEEQLRQKKNSQRSNSRFNNHNQSNSNRYSSNRRNMQNTQRDSFASTKTGSFRNNQRNARKVEEVSQAPRANMFDALMNNDGDSD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
147			G49108TO	GlyGen
308			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	Saccharomyces cerevisiae
Deadenylation of mRNA	Saccharomyces cerevisiae
L13a-mediated translational silencing of Ceruloplasmin expression	Saccharomyces cerevisiae
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Saccharomyces cerevisiae
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Saccharomyces cerevisiae
Ribosomal scanning and start codon recognition	Saccharomyces cerevisiae
Translation initiation complex formation	Saccharomyces cerevisiae
mTORC1-mediated signalling	Saccharomyces cerevisiae

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements