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Platelet-activating factor receptor

Summary

UniProt ID

P46002

Gene Symbol

Ptafr

Gene ID

58949

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P46002
Re-Glyco: P46002

Annotation

Keyword

Cell membrane
Chemotaxis
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying 1 entry
GO Term
plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 31 in total

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GO Term
negative regulation of blood pressure
response to organophosphorus
cellular response to gravity
positive regulation of maternal process involved in parturition
response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
regulation of transcription by RNA polymerase II
response to symbiotic bacterium
response to lipopolysaccharide
positive regulation of interleukin-6 production

Displaying **all 6** entries
GO Term
lipopolysaccharide binding
lipopolysaccharide immune receptor activity
platelet activating factor receptor activity
G protein-coupled purinergic nucleotide receptor activity
phospholipid binding
mitogen-activated protein kinase binding

Annotation information from UniProt.

Sequence

MEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLTVADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVAYPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPYSVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAVFVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFRKHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
4	N-linked (GlcNAc...) asparagine			UniProt
169	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Class A/1 (Rhodopsin-like receptors)	Rattus norvegicus
G alpha (q) signalling events	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus

Disease

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:10247	pleurisy	Alliance of Genome Resources
DOID:1227	neutropenia	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:2921	glomerulonephritis	Alliance of Genome Resources
DOID:3021	acute kidney failure	Alliance of Genome Resources
DOID:8677	perinatal necrotizing enterocolitis	Alliance of Genome Resources