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Ran GTPase-activating protein 1

Summary

UniProt ID: P46061
Gene Symbol: Fug1 Rangap1
Gene ID: 19387
Organism: Mus musculus (house mouse)

External Links

GlyGen: P46061
PubChem: P46061
Re-Glyco: P46061

Annotation

Keyword: 3D-structure Acetylation Centromere Chromosome Cytoskeleton GTPase activation Isopeptide bond Kinetochore Leucine-rich repeat Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
signal transduction	IEA	GO_REF
protein sumoylation	ISO	GO_REF
protein sumoylation	IEA	GO_REF
negative regulation of protein export from nucleus	ISO	GO_REF
negative regulation of protein export from nucleus	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

intercellular transport [inference]

nuclear export

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

negative regulation of protein export from nucleus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

response to axon injury

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to vasopressin [inference]

cellular response to vasopressin

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to vasopressin [inference]

cellular response to vasopressin

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to nitrogen compound [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to vasopressin [inference]

cellular response to vasopressin

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

response to vasopressin [inference]

cellular response to vasopressin

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus

cellular response to vasopressin

localization [inference]

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

nuclear export

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

negative regulation of protein export from nucleus

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

negative regulation of protein export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of transport [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of cellular process [inference]

signal transduction

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	Reference
kinetochore	ISS	GO_REF
kinetochore	ISO	GO_REF
kinetochore	IEA	GO_REF
nucleus	IBA	GO_REF
nuclear envelope	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

catalytic complex [inference]

transferase complex [inference]

SUMO ligase complex

cellular anatomical structure [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

nucleoplasm

cytoplasm

neuron projection cytoplasm [inference]

axon cytoplasm

cytosol

membrane [inference]

organelle membrane [inference]

nuclear membrane

organelle envelope [inference]

nuclear envelope

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

kinetochore

spindle [inference]

mitotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

kinetochore

spindle [inference]

mitotic spindle

perinuclear region of cytoplasm

cytoplasmic periphery of the nuclear pore complex

supramolecular complex [inference]

kinetochore

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
RNA binding	ISO	GO_REF
RNA binding	IEA	GO_REF
GTPase activator activity	ISO	GO_REF
GTPase activator activity	IBA	GO_REF
GTPase activator activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding [inference]

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

GTPase binding [inference]

small GTPase binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
411				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	Mus musculus
EML4 and NUDC in mitotic spindle formation	Mus musculus
Mitotic Prometaphase	Mus musculus
Postmitotic nuclear pore complex (NPC) reformation	Mus musculus
RHO GTPases Activate Formins	Mus musculus
Resolution of Sister Chromatid Cohesion	Mus musculus
SUMOylation of DNA replication proteins	Mus musculus
SUMOylation of nuclear envelope proteins	Mus musculus
Separation of Sister Chromatids	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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