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Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-141444

PubChem

R-MMU-141444

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 27 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
A2AGT5	Cytoskeleton-associated protein 5	Ckap5	view
O08901	Mitotic checkpoint serine/threonine-protein kinase BUB1	Bub1	view
O54692	Centromere/kinetochore protein zw10 homolog	Zw10	view
O70126	Aurora kinase B	Aik2 Aim1 Airk2 Ark2 Aurkb Stk1 Stk12 Stk5	view
O88485	Cytoplasmic dynein 1 intermediate chain 1	Dnci1 Dncic1 Dync1i1	view
P28740	Kinesin-like protein KIF2A	Kif2 Kif2a Kns2	view
P46061	Ran GTPase-activating protein 1	Fug1 Rangap1	view
P63087	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	Ppp1cc	view
Q6PFD9	Nuclear pore complex protein Nup98-Nup96	Nup98	view
Q6RT24	Centromere-associated protein E	Cenpe	view

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