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Integrin beta-1
Summary
- UniProt ID
- P49134
- Gene Symbol
-
- Itgb1
- Gene ID
- 24511
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cell projection
- Disulfide bond
- EGF-like domain
- Endosome
- Glycoprotein
- Integrin
- Isopeptide bond
- Magnesium
- Metal-binding
- Myogenesis
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| signaling receptor activity |
| signaling receptor binding |
| calcium ion binding |
| laminin binding |
| magnesium ion binding |
| protease binding |
| actin binding |
| integrin binding |
| collagen binding |
| kinase binding |
Sequence
MNLQLVFWIGLISLICSVFGQTDKNRCLKANAKSCGECIQAGPNCGWCTNTTFLQEGMPTSARCDDLEALKKKGCHPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLLLKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTDRGEFFNELVGQQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITANKCPNKESENQLKLNPLGFTEEVEVVLQFICKCNCQSHGIPASPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRENTNEIYSGKFCECDNFNCDRSNGLICGGNGVCRCRVCECYPNYTGSACDCSLDTVPCVATNGQICNGRGICECGACKCTDPKFQGPTCETCQTCLGVCAEHKECVQCRAFNKGEKKDTCAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYSVNSKGEAHVHVVETPDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 50 | N-linked (GlcNAc...) asparagine |
|
||
| 94 | N-linked (GlcNAc...) asparagine |
|
||
| 97 | N-linked (GlcNAc...) asparagine |
|
||
| 212 | N-linked (GlcNAc...) asparagine |
|
||
| 269 | N-linked (GlcNAc...) asparagine |
|
||
| 363 | N-linked (GlcNAc...) asparagine |
|
||
| 406 | N-linked (GlcNAc...) asparagine |
|
||
| 417 | N-linked (GlcNAc...) asparagine |
|
||
| 482 | N-linked (GlcNAc...) asparagine |
|
||
| 521 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| MET activates PTK2 signaling | Rattus norvegicus |
| MET interacts with TNS proteins | Rattus norvegicus |
| Molecules associated with elastic fibres | Rattus norvegicus |
| RAC1 GTPase cycle | Rattus norvegicus |
| RAC2 GTPase cycle | Rattus norvegicus |
| RHOG GTPase cycle | Rattus norvegicus |
| Signal transduction by L1 | Rattus norvegicus |
| Syndecan interactions | Rattus norvegicus |
| TGF-beta receptor signaling activates SMADs | Rattus norvegicus |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10908 | hydrocephalus | |
| DOID:5844 | myocardial infarction |
