Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
Actin, cytoplasmic 1
Summary
- UniProt ID
- P60709
- Gene Symbol
- ACTB
- Gene ID
- 60
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- 3D-structure ATP-binding Acetylation Cytoskeleton Deafness Direct protein sequencing Disease variant Dystonia Hydrolase Intellectual disability Isopeptide bond Methylation Nucleus Oxidation Proteomics identification Reference proteome Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| morphogenesis of a polarized epithelium | ||
| chromatin remodeling | ||
| chromatin remodeling | ||
| regulation of transcription by RNA polymerase II | ||
| cytoskeleton organization |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cell cycle
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| kinetochore | ||
| chromatin | ||
| chromatin | ||
| nucleosome | ||
| obsolete extracellular space |
|
|
| GO Term | Evidence Code | Reference |
|---|---|---|
| structural constituent of cytoskeleton | ||
| ATP binding |
|
|
| ATP hydrolysis activity | ||
| kinesin binding | ||
| protein kinase binding |
Sequence
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 12 |
|
|||
| 33 |
|
|||
| 60 |
|
|||
| 160 |
|
|||
| 199 |
|
|||
| 265 |
|
|||
| 271 |
|
|||
| 277 |
|
|||
| 278 |
|
|||
| 281 |
|
G41840AI
G49108TO
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of STAT3 by cadherin engagement | Homo sapiens |
| Adherens junctions interactions | Homo sapiens |
| B-WICH complex positively regulates rRNA expression | Homo sapiens |
| Cell-extracellular matrix interactions | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| DNA Damage Recognition in GG-NER | Homo sapiens |
| EPH-ephrin mediated repulsion of cells | Homo sapiens |
| EPHB-mediated forward signaling | Homo sapiens |
| FCGR3A-mediated phagocytosis | Homo sapiens |
| Factors involved in megakaryocyte development and platelet production | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1588 | thrombocytopenia | |
| DOID:0081112 | Baraitser-Winter syndrome 1 |
