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Cell division control protein 42 homolog

Summary

UniProt ID

P60953

Gene Symbol

CDC42

Organism

Homo sapiens (human)

External Links

GlyGen: P60953
PubChem: P60953
The Human Metabolome Database: HMDBP01784
The O-GlcNAc Database: P60953
RaftProt: P60953

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Cytoskeleton
Differentiation
Direct protein sequencing
Disease variant
GTP-binding
Glycoprotein
Hydrolase
Intellectual disability
Methylation
Neurogenesis
Phosphoprotein
Prenylation
Reference proteome

Gene Ontology (GO)

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GO Term
modulation by host of viral process
cardiac conduction system development
cardiac neural crest cell migration involved in outflow tract morphogenesis
endocytosis
actin filament organization
Golgi organization
regulation of mitotic nuclear division
nuclear migration
establishment or maintenance of cell polarity
protein localization

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GO Term
storage vacuole
endoplasmic reticulum membrane
centrosome
cytoplasmic ribonucleoprotein granule
focal adhesion
dendritic spine
Schaffer collateral - CA1 synapse

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GO Term
protein kinase binding
GTP-dependent protein binding
mitogen-activated protein kinase kinase kinase binding
thioesterase binding
identical protein binding
GTPase activity
G protein activity
GTP binding
GBD domain binding
apolipoprotein A-I receptor binding

Annotation information from UniProt.

Sequence

MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
32	(Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate	24141704		UniProt GlyGen
35	(Microbial infection) O-alpha-linked (GlcNAc) threonine; by C.novyi toxin TcdA; alternate	8810274		UniProt GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
RHO GTPases activate PAKs	Homo sapiens
RHOG GTPase cycle	Homo sapiens
RHOJ GTPase cycle	Homo sapiens
RHOQ GTPase cycle	Homo sapiens
RHOU GTPase cycle	Homo sapiens
RHOV GTPase cycle	Homo sapiens
Regulation of actin dynamics for phagocytic cup formation	Homo sapiens
VEGFA-VEGFR2 Pathway	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements