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Repository for lectin-assisted multimodality data
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MIRAGE
Transforming growth factor beta-2 proprotein
Summary
- UniProt ID
- P61812
- Gene Symbol
-
- TGFB2
- Gene ID
- 7042
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Aortic aneurysm
- Chromosomal rearrangement
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Growth factor
- Mitogen
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| collagen-containing extracellular matrix |
| platelet alpha granule lumen |
| extracellular region |
| extracellular space |
| axon |
| neuronal cell body |
Sequence
MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 72 | N-linked (GlcNAc...) asparagine | |||
| 140 | N-linked (GlcNAc...) asparagine | |||
| 230 |
|
|||
| 241 | N-linked (GlcNAc...) asparagine |
G02815KT
G80920RR
G62765YT
G41247ZX
G06110VR
G49108TO
G83460ZZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ECM proteoglycans | Homo sapiens |
| Molecules associated with elastic fibres | Homo sapiens |
| Platelet degranulation | Homo sapiens |
| TGF-beta receptor signaling activates SMADs | Homo sapiens |
| TGFBR3 regulates TGF-beta signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070233 | Loeys-Dietz syndrome 4 | |
| DOID:5637 | pancreatic adenosquamous carcinoma | |
| DOID:9256 | colorectal cancer |
