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MIRAGE
Rho-associated protein kinase 1
Summary
- UniProt ID
- P70335
- Gene Symbol
- Rock1
- Gene ID
- 19877
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- ATP-binding Acetylation Alternative splicing Apoptosis Cell membrane Cell projection Coiled coil Cytoskeleton Golgi apparatus Magnesium Phosphoprotein Reference proteome Serine/threonine-protein kinase Zinc-finger
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| mitotic cytokinesis | ||
| epithelial to mesenchymal transition | ||
| epithelial to mesenchymal transition | ||
| apical constriction | ||
| apoptotic process |
|
|
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| Golgi membrane | ||
| Golgi membrane | ||
| Golgi membrane | ||
| ruffle | ||
| ruffle |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| ATP binding | ||
| zinc ion binding |
|
|
Sequence
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANASENRSSSNVDKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNLKLDKIMKELDEEGNQRRNLESAVSQIEKEKMLLQHRINEYQRKVEQENEKRRNIENEVSTLKDQLEDLRKASQTSQLANEKLTQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQADKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSIQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLALQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLRKIQELQSEKETLSTQLDLAETKAESEQLARGILEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSVLTKDIEMLRKENEELNERMRTAEEEYKLKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRKDIEVEPVQQGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
Glycosylation Sites
G12261QD
G49108TO
G70696MD
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Apoptotic cleavage of cellular proteins | Mus musculus |
| EPHB-mediated forward signaling | Mus musculus |
| G alpha (12/13) signalling events | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| RHO GTPases Activate ROCKs | Mus musculus |
| RHOA GTPase cycle | Mus musculus |
| RHOB GTPase cycle | Mus musculus |
| RHOBTB1 GTPase cycle | Mus musculus |
| RHOC GTPase cycle | Mus musculus |
| RHOH GTPase cycle | Mus musculus |
