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Rho-associated protein kinase 1

Summary

UniProt ID

P70335

Gene Symbol

Rock1

Gene ID

19877

Organism

Mus musculus (house mouse)

External Links

GlyGen: P70335
PubChem: P70335
The O-GlcNAc Database: P70335
RaftProt: P70335
Re-Glyco: P70335

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell membrane
Cell projection
Coiled coil
Cytoskeleton
Golgi apparatus
Magnesium
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Zinc-finger

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
cytoskeleton
plasma membrane
Golgi membrane
ruffle
centriole
cytoplasmic stress granule
lamellipodium
bleb
Schaffer collateral - CA1 synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 39 in total

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GO Term
regulation of microtubule cytoskeleton organization
positive regulation of gene expression
negative regulation of angiogenesis
regulation of cell migration
bleb assembly
positive regulation of dephosphorylation
regulation of keratinocyte differentiation
positive regulation of autophagy
actin cytoskeleton organization
apical constriction

Displaying entries **1 - 10** of 25 in total

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GO Term
histone H3S10 kinase activity
histone H3T11 kinase activity
histone H3T6 kinase activity
histone H3S28 kinase activity
histone H2AS1 kinase activity
Rho-dependent protein serine/threonine kinase activity
protein serine/threonine kinase activity
ATP binding
protein serine kinase activity
metal ion binding

Annotation information from UniProt.

Sequence

MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANASENRSSSNVDKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNLKLDKIMKELDEEGNQRRNLESAVSQIEKEKMLLQHRINEYQRKVEQENEKRRNIENEVSTLKDQLEDLRKASQTSQLANEKLTQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQADKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSIQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLALQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLRKIQELQSEKETLSTQLDLAETKAESEQLARGILEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSVLTKDIEMLRKENEELNERMRTAEEEYKLKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRKDIEVEPVQQGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites