SMAD family member 4
| GO Term | Evidence Code | Reference |
|---|---|---|
| atrioventricular valve formation | ||
| epithelial to mesenchymal transition involved in endocardial cushion formation | ||
| left ventricular cardiac muscle tissue morphogenesis | ||
| obsolete positive regulation of cell proliferation involved in heart valve morphogenesis |
|
|
| cardiac septum development |
| Pathway Name | Organism |
|---|---|
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | Mus musculus |
| FOXO-mediated transcription of cell cycle genes | Mus musculus |
| RUNX2 regulates bone development | Mus musculus |
| RUNX3 regulates CDKN1A transcription | Mus musculus |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | Mus musculus |
| Signaling by Activin | Mus musculus |
| Signaling by BMP | Mus musculus |
| Signaling by NODAL | Mus musculus |
| TGF-beta receptor signaling activates SMADs | Mus musculus |
| Ub-specific processing proteases | Mus musculus |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12347 | osteogenesis imperfecta | |
| DOID:0050787 | juvenile polyposis syndrome |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
GlyCosmos Portal v4.5.0
Last updated: April 6, 2026