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MIRAGE
C5a anaphylatoxin chemotactic receptor 1
Summary
- UniProt ID
- P97520
- Gene Symbol
-
- C5ar1
- C5r1
- Gene ID
- 113959
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Chemotaxis
- Cytoplasmic vesicle
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Sulfation
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cytoplasmic vesicle |
| cell surface |
| basolateral plasma membrane |
| apical part of cell |
| GO Term |
|---|
| G protein-coupled receptor activity |
| complement component C5a binding |
| complement component C5a receptor activity |
Sequence
MDPISNDSSEITYDYSDGTPNPDMPADGVYIPKMEPGDIAALIIYLAVFLVGVTGNALVVWVTAFEAKRTVNAIWFLNLAVADLLSCLALPILFTSIVKHNHWPFGDQACIVLPSLILLNMYSSILLLATISADRFLLVFKPIWCQKFRRPGLAWMACGVTWVLALLLTIPSFVFRRIHKDPYSDSILCNIDYSKGPFFIEKAIAILRLMVGFVLPLLTLNICYTFLLIRTWSRKATRSTKTLKVVMAVVTCFFVFWLPYQVTGVILAWLPRSSSTFQSVERLNSLCVSLAYINCCVNPIIYVMAGQGFHGRLRRSLPSIIRNVLSEDSLGRDSKSFTRSTMDTSTQKSQAV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 6 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (i) signalling events | Rattus norvegicus |
| Neutrophil degranulation | Rattus norvegicus |
| Peptide ligand-binding receptors | Rattus norvegicus |
| Regulation of Complement cascade | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060903 | thrombosis | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:1227 | neutropenia | |
| DOID:332 | amyotrophic lateral sclerosis | |
| DOID:9970 | obesity |
