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MIRAGE
adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying all 10 entries
Gene ID Gene Symbol Description Source
259 AMBP alpha-1-microglobulin/bikunin precursor
3952 LEP leptin
4049 LTA lymphotoxin alpha
4153 MBL2 mannose binding lectin 2
4638 MYLK myosin light chain kinase
5328 PLAU plasminogen activator, urokinase
6439 SFTPB surfactant protein B
6440 SFTPC surfactant protein C
7124 TNF tumor necrosis factor
7133 TNFRSF1B TNF receptor superfamily member 1B
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24795 Serpina3n serpin family A member 3N
24816 Tbxa2r thromboxane A2 receptor
60582 Il1rn interleukin 1 receptor antagonist
84007 C3ar1 complement C3a receptor 1
113959 C5ar1 complement C5a receptor 1
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025