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MIRAGE
Pulmonary surfactant-associated protein B
Summary
- UniProt ID
- P07988
- Gene Symbol
- SFTPB SFTP3
- Gene ID
- 6439
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- 3D-structure Direct protein sequencing Disease variant Disulfide bond Glycoprotein Proteomics identification Reference proteome Repeat Signal Surface film
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| sphingolipid metabolic process | ||
| respiratory gaseous exchange by respiratory system | ||
| animal organ morphogenesis |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
| lysosome | ||
| multivesicular body |
Sequence
MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective CSF2RA causes SMDP4 | Homo sapiens |
| Defective CSF2RB causes SMDP5 | Homo sapiens |
| Defective pro-SFTPB causes SMDP1 and RDS | Homo sapiens |
| Surfactant metabolism | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:3082 | interstitial lung disease | |
| DOID:11650 | bronchopulmonary dysplasia | |
| DOID:12716 | newborn respiratory distress syndrome | |
| DOID:3907 | lung squamous cell carcinoma | |
| DOID:11162 | respiratory failure | |
| DOID:14115 | toxic shock syndrome | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:552 | pneumonia | |
| DOID:3770 | pulmonary fibrosis |
