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toxic shock syndrome
Summary
- Synonym
-
- TSS
- toxic shock
- Definition
- A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
- Super Class
- commensal bacterial infectious disease
External Links
- Disease Ontology
- DOID:14115
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 154 | ADRB2 | adrenoceptor beta 2 | |
| 462 | SERPINC1 | serpin family C member 1 | |
| 710 | SERPING1 | serpin family G member 1 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 3304 | HSPA1B | heat shock protein family A (Hsp70) member 1B | |
| 3557 | IL1RN | interleukin 1 receptor antagonist | |
| 3586 | IL10 | interleukin 10 | |
| 4153 | MBL2 | mannose binding lectin 2 | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 5624 | PROC | protein C, inactivator of coagulation factors Va and VIIIa |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P01008 | Antithrombin-III | |
| P04070 | Vitamin K-dependent protein C | |
| P05121 | Plasminogen activator inhibitor 1 | |
| P05155 | Plasma protease C1 inhibitor | |
| P07550 | Beta-2 adrenergic receptor | |
| P07988 | Pulmonary surfactant-associated protein B | |
| P10646 | Tissue factor pathway inhibitor | |
| P11226 | Mannose-binding protein C | |
| P12821 | Angiotensin-converting enzyme | |
| P18510 | Interleukin-1 receptor antagonist protein |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P06238 | Alpha-2-macroglobulin | |
| P34978 | Thromboxane A2 receptor |
