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MIRAGE
Beta-2 adrenergic receptor

Summary
UniProt ID
P07550
Gene Symbol
  • ADRB2
  • ADRB2R
  • B2AR
Gene ID
154
Organism
Homo sapiens (human)
GlyGen
P07550
PubChem
P07550
The Human Metabolome Database
HMDBP01634
The O-GlcNAc Database
P07550
Re-Glyco
P07550
Annotation
Keyword
  • 3D-structure
  • Cell membrane
  • Disulfide bond
  • Endosome
  • G-protein coupled receptor
  • Glycoprotein
  • Golgi apparatus
  • Hydroxylation
  • Palmitate
  • Phosphoprotein
  • Reference proteome
  • Transmembrane helix
  • Ubl conjugation
Gene Ontology (GO)
Displaying entries 1 - 10 of 12 in total
GO Term
neuronal dense core vesicle
nucleus
lysosome
plasma membrane
membrane
receptor complex
endosome
early endosome
Golgi apparatus
apical plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
6 N-linked (GlcNAc...) asparagine
15 N-linked (GlcNAc...) asparagine
146
187
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Adrenoceptors Homo sapiens
Cargo recognition for clathrin-mediated endocytosis Homo sapiens
Clathrin-mediated endocytosis Homo sapiens
G alpha (s) signalling events Homo sapiens
Ub-specific processing proteases Homo sapiens
Disease
Displaying entries 1 - 10 of 22 in total
DO ID Disease Name Source
DOID:0014667 disease of metabolism
DOID:1067 open-angle glaucoma
DOID:1070 primary open angle glaucoma
DOID:10763 hypertension
DOID:11396 pulmonary edema
DOID:12361 Graves' disease
DOID:13810 familial hypercholesterolemia
DOID:13949 interstitial cystitis
DOID:14115 toxic shock syndrome
DOID:1485 cystic fibrosis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025