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Adrenoceptors

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-390696

PubChem

R-HSA-390696

Description

The adrenoceptors (adrenergic receptors) are targets for the catecholamines adrenaline (epinephrine) and noradrenaline (norepinephrine). These receptors are widespread in the body and binding of catecholamines produces a sympathetic response ('flight-or-fight response') resulting in increased heart rate, pupil dilation and energy mobilization amongst other responses. There are three major types of adrenoceptor, alpha1, alpha2 and beta. Each type is thought to have three subtypes; alpha1 (1A,1B,1D), alpha2 (2A,2B,2C) and beta (1,2,3) (Bylund DB et al, 1994).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 8** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P07550	Beta-2 adrenergic receptor	ADRB2 ADRB2R B2AR	view
P08588	Beta-1 adrenergic receptor	ADRB1 ADRB1R B1AR	view
P08913	Alpha-2A adrenergic receptor	ADRA2A ADRA2R ADRAR	view
P13945	Beta-3 adrenergic receptor	ADRB3 ADRB3R B3AR	view
P18825	Alpha-2C adrenergic receptor	ADRA2C ADRA2L2 ADRA2RL2	view
P25100	Alpha-1D adrenergic receptor	ADRA1A ADRA1D	view
P35348	Alpha-1A adrenergic receptor	ADRA1A ADRA1C	view
P35368	Alpha-1B adrenergic receptor	ADRA1B	view

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