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MIRAGE
Glutamate receptor ionotropic, NMDA 2A
Summary
- UniProt ID
- Q00959
- Gene Symbol
- Grin2a
- Gene ID
- 24409
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- 3D-structure Calcium Cell membrane Cell projection Cytoplasmic vesicle Disulfide bond Glycoprotein Ligand-gated ion channel Magnesium Metal-binding Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Transmembrane helix Zinc
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| action potential | ||
| receptor recycling | ||
| startle response | ||
| response to amphetamine | ||
| calcium ion transport |
GO Hierarchy
- rhythmic process
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytoplasm | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane | ||
| endoplasmic reticulum membrane | ||
| plasma membrane |
| GO Term | Evidence Code | Reference |
|---|---|---|
| glutamate-gated receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity |
GO Hierarchy
molecular function
transporter activity [inference]
Sequence
MGRLGYWTLLVLPALLVWRDPAQNAAAEKGPPALNIAVLLGHSHDVTERELRNLWGPEQATGLPLDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSQTFIPILGIHGGASMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGYRDFISFIKTTVDNSFVGWDMQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGLGILTTAASSMLEKFSYIPEAKASCYGQAEKPETPLHTLHQFMVNVTWDGKDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENQTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFASTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLRFCFTGVCSDRPGLLFSISRGIYSCIHGVHIEEKKKSPDFNLTGSQSNMLKLLRSAKNISNMSNMNSSRMDSPKRATDFIQRGSLIVDMVSDKGNLIYSDNRSFQGKDSIFGDNMNELQTFVANRHKDNLSNYVFQGQHPLTLNESNPNTVEVAVSTESKGNSRPRQLWKKSMESLRQDSLNQNPVSQRDEKTAENRTHSLKSPRYLPEEVAHSDISETSSRATCHREPDNNKNHKTKDNFKRSMASKYPKDCSDVDRTYMKTKASSPRDKIYTIDGEKEPSFHLDPPQFVENITLPENVGFPDTYQDHNENFRKGDSTLPMNRNPLHNEDGLPNNDQYKLYAKHFTLKDKGSPHSEGSDRYRQNSTHCRSCLSNLPTYSGHFTMRSPFKCDACLRMGNLYDIDEDQMLQETGNPATREEVYQQDWSQNNALQFQKNKLRINRQHSYDNILDKPREIDLSRPSRSISLKDRERLLEGNLYGSLFSVPSSKLLGNKSSLFPQGLEDSKRSKSLLPDHASDNPFLHTYGDDQRLVIGRCPSDPYKHSLPSQAVNDSYLRSSLRSTASYCSRDSRGHSDVYISEHVMPYAANKNTMYSTPRVLNSCSNRRVYKKMPSIESDV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 75 |
|
|
||
| 340 |
|
|
||
| 380 |
|
|||
| 443 |
|
|
||
| 444 |
|
|||
| 541 |
|
|
||
| 687 |
|
|
G30159WR
G88725PI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly and cell surface presentation of NMDA receptors | Rattus norvegicus |
| Synaptic adhesion-like molecules | Rattus norvegicus |
| Unblocking of NMDA receptors, glutamate binding and activation | Rattus norvegicus |
