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Glutamate receptor ionotropic, NMDA 2B

Summary

UniProt ID

Q00960

Gene Symbol

Grin2b

Gene ID

24410

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q00960
PubChem: Q00960
Re-Glyco: Q00960

Annotation

Keyword

3D-structure
Calcium
Cell membrane
Cytoskeleton
Direct protein sequencing
Disulfide bond
Endosome
Glycoprotein
Ligand-gated ion channel
Lysosome
Magnesium
Metal-binding
Phosphoprotein
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix
Zinc

Gene Ontology (GO)

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GO Term
cytoplasm
lysosome
cytoskeleton
plasma membrane
membrane
hippocampal mossy fiber to CA3 synapse
glutamatergic synapse
parallel fiber to Purkinje cell synapse
neuron projection
neuronal cell body

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 77 in total

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GO Term
positive regulation of synaptic transmission, glutamatergic
response to cytokine
synaptic transmission, glutamatergic
rhythmic process
detection of mechanical stimulus involved in sensory perception of pain
response to other organism
sensory organ development
long-term memory
regulation of synaptic plasticity
response to amphetamine

Displaying entries **1 - 10** of 24 in total

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GO Term
signaling receptor binding
zinc ion binding
interleukin-1 receptor binding
extracellularly glutamate-gated ion channel activity
NMDA glutamate receptor activity
scaffold protein binding
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
protein tyrosine kinase binding
glutamate-gated receptor activity
beta-catenin binding

Annotation information from UniProt.

Sequence

MKPSAECCSPKFWLVLAVLAVSGSKARSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRNLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLGAAMALSLITFICEHLFYWQFRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEERQSVMNSPTATMNNTHSNILRLLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSYNNPPCEENLFSDYISEVERTFGNLQLKDSNVYQDHYHHHHRPHSIGSTSSIDGLYDCDNPPFTTQPRSISKKPLDIGLPSSKHSQLSDLYGKFSFKSDRYSGHDDLIRSDVSDISTHTVTYGNIEGNAAKRRKQQYKDSLKKRPASAKSRREFDEIELAYRRRPPRSPDHKRYFRDKEGLRDFYLDQFRTKENSPHWEHVDLTDIYKERSDDFKRDSVSGGGPCTNRSHLKHGTGEKHGVVGGVPAPWEKNLTNVDWEDRSGGNFCRSCPSKLHNYSSTVAGQNSGRQACIRCEACKKAGNLYDISEDNSLQELDQPAAPVAVTSNASSTKYPQSPTNSKAQKKNRNKLRRQHSYDTFVDLQKEEAALAPRSVSLKDKGRFMDGSPYAHMFEMPAGESSFANKSSVPTAGHHHNNPGSGYMLSKSLYPDRVTQNPFIPTFGDDQCLLHGSKSYFFRQPTVAGASKTRPDFRALVTNKPVVVTLHGAVPGRFQKDICIGNQSNPCVPNNKNPRAFNGSSNGHVYEKLSSIESDV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
74	N-linked (GlcNAc...) asparagine	19910922 24876489	G19379ID G68318VE G88725PI	UniProt GlyGen
341	N-linked (GlcNAc...) asparagine	19910922 24876489	G41247ZX	UniProt GlyGen
348	N-linked (GlcNAc...) asparagine		G80920RR G62765YT	UniProt GlyGen
444	N-linked (GlcNAc...) asparagine		G88725PI	UniProt GlyGen
491	N-linked (GlcNAc...) asparagine			UniProt GlyGen
542	N-linked (GlcNAc...) asparagine			UniProt GlyGen
688	N-linked (GlcNAc...) asparagine	24876489	G60230HH G80920RR G14548ZL G62765YT G09775CH G31852PQ G37135JQ G41247ZX G80966KZ G02815KT G55220VL	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Assembly and cell surface presentation of NMDA receptors	Rattus norvegicus
EPHB-mediated forward signaling	Rattus norvegicus
RAF/MAP kinase cascade	Rattus norvegicus
Synaptic adhesion-like molecules	Rattus norvegicus
Unblocking of NMDA receptors, glutamate binding and activation	Rattus norvegicus

Disease

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050696	fetal alcohol spectrum disorder	Alliance of Genome Resources
DOID:1094	attention deficit hyperactivity disorder	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:9279	hyperhomocysteinemia	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements