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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glutamate receptor ionotropic, NMDA 1
Summary
- UniProt ID
- Q05586
- Gene Symbol
-
- GRIN1
- NMDAR1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q05586
- PubChem
- Q05586
- The Human Metabolome Database
- HMDBP01635
- The O-GlcNAc Database
- Q05586
- O-GlcNAcAtlas
- Q05586
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell membrane
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Intellectual disability
- Ligand-gated ion channel
- Magnesium
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of transcription by RNA polymerase II |
| visual learning |
| positive regulation of calcium ion transport into cytosol |
| GO Term |
|---|
| terminal bouton |
| synapse |
| postsynaptic membrane |
| dendrite |
| excitatory synapse |
| synaptic membrane |
Sequence
MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 61 | N-linked (GlcNAc...) asparagine |
|
||
| 203 | N-linked (GlcNAc...) asparagine |
|
||
| 205 |
|
|||
| 239 | N-linked (GlcNAc...) asparagine |
|
||
| 276 | N-linked (GlcNAc...) asparagine |
|
||
| 300 | N-linked (GlcNAc...) asparagine | |||
| 350 | N-linked (GlcNAc...) asparagine |
|
||
| 368 | N-linked (GlcNAc...) asparagine |
|
||
| 440 | N-linked (GlcNAc...) asparagine |
|
||
| 471 | N-linked (GlcNAc...) asparagine |
G49108TO
G31852PQ
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly and cell surface presentation of NMDA receptors | Homo sapiens |
| EPHB-mediated forward signaling | Homo sapiens |
| Long-term potentiation | Homo sapiens |
| Negative regulation of NMDA receptor-mediated neuronal transmission | Homo sapiens |
| Neurexins and neuroligins | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| Ras activation upon Ca2+ influx through NMDA receptor | Homo sapiens |
| Synaptic adhesion-like molecules | Homo sapiens |
| Unblocking of NMDA receptors, glutamate binding and activation | Homo sapiens |
