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MIRAGE
Prostaglandin G/H synthase 2

Summary
UniProt ID
Q05769
Gene Symbol
  • Cox-2
  • Cox2
  • Pghs-b
  • Ptgs2
  • Tis10
Gene ID
19225
Organism
Mus musculus (house mouse)
GlyConnect
GlyGen
Q05769
PubChem
Q05769
SwissLipids
Re-Glyco
Q05769
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Dioxygenase
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Heme
  • Membrane
  • Microsome
  • Nucleus
  • Peroxidase
  • Prostaglandin biosynthesis
  • Reference proteome
  • S-nitrosylation
  • Signal
Gene Ontology (GO)
Displaying all 7 entries
GO Term
neuron projection
endoplasmic reticulum membrane
nuclear inner membrane
nuclear outer membrane
caveola
cytoplasm
protein-containing complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Site Annotations
Displaying 1 entry
Position Description
592 Not glycosylated
Annotation information from UniProt.
Sequence
MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
53 N-linked (GlcNAc...) asparagine
130 N-linked (GlcNAc...) asparagine
396 N-linked (GlcNAc...) asparagine
580 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 7 entries
Pathway Name Organism
Biosynthesis of DHA-derived SPMs Mus musculus
Biosynthesis of DPAn-3 SPMs Mus musculus
Biosynthesis of EPA-derived SPMs Mus musculus
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives Mus musculus
Nicotinamide salvaging Mus musculus
Synthesis of 15-eicosatetraenoic acid derivatives Mus musculus
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Mus musculus
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025